Ann Logan

Good lighting makes or breaks a cross stitch project. Proper lighting prevents floss color confusion. Adequate lighting prevents improper stitch placement. It also makes the chart much easier to read. Light sources do not have to be expensive.

I assume that you yourself understand this, but still I will say. It is very important to wash your hands before touching the fabric or thread. Of course, you are going to wash the finished cross stitch design, but why make it dirtier?
In case you use a thread or fabric that is hand-dyed wash them in advance so that they do not stain your handwork.
Unwind your thread from time to time. Just leave the needle and let the thread loose - it will unwind itself... Or help it a little to unwind.
Do this every few stitches, otherwise the texture will be uneven and the fabric will show through your stitches too much.